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House dust mite induced allergic airway disease is attenuated in CD11c(cre)IL-4Rα(−/l)°(x) mice

The precise mechanisms leading to development of T helper type (Th)2-driven allergic responses are unknown. We aimed to determine how IL-4 receptor alpha (IL-4Rα) signaling on CD11c(+) cells influences allergen-induced Th2 responses in mice. CD11c(cre)IL-4Rα(−/l)°(x) mice, deficient in IL-4Rα on den...

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Detalles Bibliográficos
Autores principales:	Nieuwenhuizen, Natalie Eva, Kirstein, Frank, Hoving, Jennifer Claire, Brombacher, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772663/ https://www.ncbi.nlm.nih.gov/pubmed/29343807 http://dx.doi.org/10.1038/s41598-017-19060-9

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