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miR-133b induces chemoresistance of osteosarcoma cells to cisplatin treatment by promoting cell death, migration and invasion

As an important chemotherapeutic agent for the treatment of osteosarcoma, the effectiveness of cisplatin is considered to be due to its unique properties, which allow it to penetrate the cell membrane and form various DNA-platinum adducts, resulting in genetic alterations or DNA damage. However, che...

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Detalles Bibliográficos
Autores principales: Zou, Yonggen, Yang, Jiexiang, Wu, Jian, Luo, Cheng, Huang, Yuanshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772689/
https://www.ncbi.nlm.nih.gov/pubmed/29399170
http://dx.doi.org/10.3892/ol.2017.7432