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Microdosimetric Modeling of Biological Effectiveness for Boron Neutron Capture Therapy Considering Intra- and Intercellular Heterogeneity in (10)B Distribution

We here propose a new model for estimating the biological effectiveness for boron neutron capture therapy (BNCT) considering intra- and intercellular heterogeneity in (10)B distribution. The new model was developed from our previously established stochastic microdosimetric kinetic model that determi...

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Detalles Bibliográficos
Autores principales: Sato, Tatsuhiko, Masunaga, Shin-ichiro, Kumada, Hiroaki, Hamada, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772701/
https://www.ncbi.nlm.nih.gov/pubmed/29343841
http://dx.doi.org/10.1038/s41598-017-18871-0