Lentiviral delivery of CTLA-4 shRNA improves the expansion of cytokine-induced killer cells and enhances cytotoxic activity in vitro

Cytokine-induced killer (CIK) cells are in vitro-expanded cells harboring potent toxicity against tumor cells. Recently, it was identified that the cytotoxicity and proliferation of CIK cells are restricted by a prolonged CIK cell culture period. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)...

Descripción completa

Detalles Bibliográficos
Autores principales: Rui, Tao, Cheng, Xiangdong, Wu, Hao, Wang, Fuwei, Ye, Zaiyuan, Wu, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772746/
https://www.ncbi.nlm.nih.gov/pubmed/29399145
http://dx.doi.org/10.3892/ol.2017.7376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772746/
https://www.ncbi.nlm.nih.gov/pubmed/29399145
http://dx.doi.org/10.3892/ol.2017.7376

Ejemplares similares