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Mutant-allele fraction heterogeneity is associated with non-small cell lung cancer patient survival

Genetic intratumor heterogeneity is associated with tumor occurrence, development and overall outcome. The present study aims to explore the association between mutant-allele fraction (MAF) heterogeneity and patient overall survival in lung cancer. Somatic mutation data of 939 non-small cell lung ca...

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Detalles Bibliográficos
Autores principales: Shen, Sipeng, Wei, Yongyue, Zhang, Ruyang, Du, Mulong, Duan, Weiwei, Yang, Sheng, Zhao, Yang, Christiani, David C., Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772758/
https://www.ncbi.nlm.nih.gov/pubmed/29399148
http://dx.doi.org/10.3892/ol.2017.7428