Lysosome-associated membrane protein 2 (LAMP-2) expression induced by miR-194-5p downregulation contributes to sunitinib resistance in human renal cell carcinoma cells

Sunitinib is a tyrosine kinase inhibitor that is used as the primary treatment in metastatic renal cell carcinoma (RCC). The main difficulty associated with its use is the development of drug resistance. In the present study, ACHN cells, a human renal cell carcinoma cell line, were used to establish...

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Detalles Bibliográficos
Autores principales: Yumioka, Tetsuya, Osaki, Mitsuhiko, Sasaki, Ryo, Yamaguchi, Noriya, Onuma, Kunishige, Iwamoto, Hideto, Morizane, Shuichi, Honda, Masashi, Takenaka, Atsushi, Okada, Futoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772808/
https://www.ncbi.nlm.nih.gov/pubmed/29399154
http://dx.doi.org/10.3892/ol.2017.7423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772808/
https://www.ncbi.nlm.nih.gov/pubmed/29399154
http://dx.doi.org/10.3892/ol.2017.7423

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