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SDHB downregulation facilitates the proliferation and invasion of colorectal cancer through AMPK functions excluding those involved in the modulation of aerobic glycolysis

Loss-of-function of succinate dehydrogenase-B (SDHB) is a predisposing factor of aerobic glycolysis and cancer progression. Adenosine monophosphate activated protein kinase (AMPK) is involved in the regulation of aerobic glycolysis and the diverse hallmarks of cancer. The present study investigated...

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Detalles Bibliográficos
Autores principales: Xiao, Zhiming, Liu, Shaojun, Ai, Feiyan, Chen, Xiong, Li, Xiayu, Liu, Rui, Ren, Weiguo, Zhang, Xuemei, Shu, Peng, Zhang, Decai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772827/
https://www.ncbi.nlm.nih.gov/pubmed/29399091
http://dx.doi.org/10.3892/etm.2017.5482