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Loperamide, an antidiarrheal agent, induces apoptosis and DNA damage in leukemia cells

Loperamide, an antidiarrheal agent, is frequently used to treat patients with leukemia with symptoms of diarrhea during treatment. However, the effect of loperamide on leukemia cells is unknown. The MTT assay was used to explore the cytotoxic effect of loperamide on leukemia cells. Morphological ana...

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Detalles Bibliográficos
Autores principales: He, Xin, Zhu, Lei, Li, Shu, Chen, Zhigang, Zhao, Xiaoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772836/
https://www.ncbi.nlm.nih.gov/pubmed/29399146
http://dx.doi.org/10.3892/ol.2017.7435