Apelin Ameliorates High Glucose-Induced Downregulation of Connexin 43 via AMPK-Dependent Pathway in Neonatal Rat Cardiomyocytes

Diabetes Mellitus is a common disorder, with increasing risk of cardiac arrhythmias. Studies have shown that altered connexin expression and gap junction remodeling under hyperglycemia contribute to the high prevalence of cardiac arrhythmias and even sudden death. Connexin 43 (Cx43), a major protein...

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Detalles Bibliográficos
Autores principales: Li, Xiaoting, Yu, Lu, Gao, Jing, Bi, Xukun, Zhang, Juhong, Xu, Shiming, Wang, Meihui, Chen, Mengmeng, Qiu, Fuyu, Fu, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2018
Materias:
Orginal Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772859/
https://www.ncbi.nlm.nih.gov/pubmed/29392082
http://dx.doi.org/10.14336/AD.2017.0426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772859/
https://www.ncbi.nlm.nih.gov/pubmed/29392082
http://dx.doi.org/10.14336/AD.2017.0426

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