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Apelin Ameliorates High Glucose-Induced Downregulation of Connexin 43 via AMPK-Dependent Pathway in Neonatal Rat Cardiomyocytes
Diabetes Mellitus is a common disorder, with increasing risk of cardiac arrhythmias. Studies have shown that altered connexin expression and gap junction remodeling under hyperglycemia contribute to the high prevalence of cardiac arrhythmias and even sudden death. Connexin 43 (Cx43), a major protein...
Autores principales: | Li, Xiaoting, Yu, Lu, Gao, Jing, Bi, Xukun, Zhang, Juhong, Xu, Shiming, Wang, Meihui, Chen, Mengmeng, Qiu, Fuyu, Fu, Guosheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772859/ https://www.ncbi.nlm.nih.gov/pubmed/29392082 http://dx.doi.org/10.14336/AD.2017.0426 |
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