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Salidroside attenuates hypoxia/reoxygenation-induced human brain vascular smooth muscle cell injury by activating the SIRT1/FOXO3α pathway

It has been reported that salidroside (SAL), a natural dietary isothiocyanate, exhibits neuroprotective roles in cerebral ischemia-reperfusion injury. However, to the best of our knowledge, its underlying protective mechanism remains unknown. Sirtuin 1 (SIRT1) is a class III histone deacetylase invo...

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Detalles Bibliográficos
Autores principales: Xu, Lina, Jia, Longbin, Wang, Qingyun, Hou, Jing, Li, Shifang, Teng, Junfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772920/
https://www.ncbi.nlm.nih.gov/pubmed/29434685
http://dx.doi.org/10.3892/etm.2017.5446