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A phase I clinical trial of dTCApFs, a derivative of a novel human hormone peptide, for the treatment of advanced/metastatic solid tumors

The aim of the present phase I first-in-human study was to investigate the safety/efficacy of dTCApFs (a novel hormone peptide that enters cells through the T1/ST2 receptor), in advanced/metastatic solid tumors. The primary objective of this open-label dose-escalation study was to determine the safe...

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Detalles Bibliográficos
Autores principales: Stemmer, Salomon M., Benjaminov, Ofer, Silverman, Michael H., Sandler, Uziel, Purim, Ofer, Sender, Naomi, Meir, Chen, Oren-Apoteker, Pnina, Ohana, Joel, Devary, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772927/
https://www.ncbi.nlm.nih.gov/pubmed/29423221
http://dx.doi.org/10.3892/mco.2017.1505