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The inhibitory roles of Ihh downregulation on chondrocyte growth and differentiation

The proliferative rate of chondrocytes affects bone elongation. Chondrocyte hypertrophy is required for endochondral bone formation as chondrocytes secrete factors required for osteoblast differentiation and maturation. Previous studies have demonstrated that the Indian hedgehog (Ihh) signaling path...

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Detalles Bibliográficos
Autores principales: Deng, Ang, Zhang, Hongqi, Hu, Minyu, Liu, Shaohua, Wang, Yuxiang, Gao, Qile, Guo, Chaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772930/
https://www.ncbi.nlm.nih.gov/pubmed/29434683
http://dx.doi.org/10.3892/etm.2017.5458