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Upregulation of Bcl2 in NSCLC with acquired resistance to EGFR-TKI

Lung cancer has the highest incidence and mortality rate worldwide among all malignancy-associated mortalities, of which non-small cell lung cancer accounts for 80% of all cases. Resistance against epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) develops following 8–12 months...

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Detalles Bibliográficos
Autores principales: Cheong, Hio Teng, Xu, Fei, Choy, Chi Tung, Hui, Connie Wun Chun, Mok, Tony Shu Kam, Wong, Chi Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772989/
https://www.ncbi.nlm.nih.gov/pubmed/29422965
http://dx.doi.org/10.3892/ol.2017.7377