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Mass-spectrometric profiling of cerebrospinal fluid reveals metabolite biomarkers for CNS involvement in varicella zoster virus reactivation

BACKGROUND: Varicella zoster virus (VZV) reactivation spans the spectrum from uncomplicated segmental herpes zoster to life-threatening disseminated CNS infection. Moreover, in the absence of a small animal model for this human pathogen, studies of pathogenesis at the organismal level depend on anal...

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Detalles Bibliográficos
Autores principales: Kuhn, Maike, Sühs, Kurt-Wolfram, Akmatov, Manas K., Klawonn, Frank, Wang, Junxi, Skripuletz, Thomas, Kaever, Volkhard, Stangel, Martin, Pessler, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773076/
https://www.ncbi.nlm.nih.gov/pubmed/29343258
http://dx.doi.org/10.1186/s12974-017-1041-0