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Histological subtypes of mouse mammary tumors reveal conserved relationships to human cancers

Human breast cancer has been characterized by extensive transcriptional heterogeneity, with dominant patterns reflected in the intrinsic subtypes. Mouse models of breast cancer also have heterogeneous transcriptomes and we noted that specific histological subtypes were associated with particular sub...

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Detalles Bibliográficos
Autores principales: Hollern, Daniel P., Swiatnicki, Matthew R., Andrechek, Eran R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773092/
https://www.ncbi.nlm.nih.gov/pubmed/29346386
http://dx.doi.org/10.1371/journal.pgen.1007135