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Computational study of HIV gp120 as a target for polyanionic entry inhibitors: Exploiting the V3 loop region

Multiple approaches are being utilized to develop therapeutics to treat HIV infection. One approach is designed to inhibit entry of HIV into host cells, with a target being the viral envelope glycoprotein, gp120. Polyanionic compounds have been shown to be effective in inhibiting HIV entry, with a m...

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Detalles Bibliográficos
Autores principales: Hollingsworth, Louis R., Brown, Anne M., Gandour, Richard D., Bevan, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773097/
https://www.ncbi.nlm.nih.gov/pubmed/29346393
http://dx.doi.org/10.1371/journal.pone.0190658