6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related protein TTR-33

Oxidative stress is linked to many pathological conditions including the loss of dopaminergic neurons in Parkinson’s disease. The vast majority of disease cases appear to be caused by a combination of genetic mutations and environmental factors. We screened for genes protecting Caenorhabditis elegan...

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Detalles Bibliográficos
Autores principales: Offenburger, Sarah-Lena, Ho, Xue Yan, Tachie-Menson, Theresa, Coakley, Sean, Hilliard, Massimo A., Gartner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773127/
https://www.ncbi.nlm.nih.gov/pubmed/29346382
http://dx.doi.org/10.1371/journal.pgen.1007125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773127/
https://www.ncbi.nlm.nih.gov/pubmed/29346382
http://dx.doi.org/10.1371/journal.pgen.1007125

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