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Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise

With the increasing number of therapeutic strategies tested in humans to reduce the size of the latent reservoir, the development of a robust, precise and clinical trial scalable assay that measures the frequency of infected cells carrying inducible replication-competent HIV is urgently needed. The...

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Detalles Bibliográficos
Autores principales: Plantin, Johann, Massanella, Marta, Chomont, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773137/
https://www.ncbi.nlm.nih.gov/pubmed/29343255
http://dx.doi.org/10.1186/s12977-017-0385-y