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P-MAPA immunotherapy potentiates the effect of cisplatin on serous ovarian carcinoma through targeting TLR4 signaling

BACKGROUND: Toll-like receptors (TLRs) are transmembrane proteins expressed on the surface of ovarian cancer (OC) and immune cells. Identifying the specific roles of the TLR-mediated signaling pathways in OC cells is important to guide new treatments. Because immunotherapies have emerged as the adju...

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Detalles Bibliográficos
Autores principales: de Almeida Chuffa, Luiz Gustavo, de Moura Ferreira, Grazielle, Lupi, Luiz Antonio, da Silva Nunes, Iseu, Fávaro, Wagner José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773141/
https://www.ncbi.nlm.nih.gov/pubmed/29343281
http://dx.doi.org/10.1186/s13048-018-0380-5