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MicroRNA-10b regulates epithelial–mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma

BACKGROUND: Our previous work showed that miR-10b was overexpressed in hepatocellular carcinoma (HCC) and promoted HCC cell migration and invasion. Epithelial–mesenchymal transition (EMT) is involved in HCC metastasis. So, we suspected that miR-10b might participate in the HCC EMT. METHODS: We perfo...

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Detalles Bibliográficos
Autores principales: Hujie, Gulibaha, Zhou, Sheng-hua, Zhang, Hua, Qu, Jie, Xiong, Xiao-wei, Hujie, Outikuer, Liao, Cheng-gong, Yang, Shun-e
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773153/
https://www.ncbi.nlm.nih.gov/pubmed/29375271
http://dx.doi.org/10.1186/s12935-018-0508-0