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Structural basis for the molecular interactions in DNA damage tolerances

DNA damage tolerance (DDT) is a cell function to avoid replication arrest by DNA damage during DNA replication. DDT includes two pathways, translesion DNA synthesis (TLS) and template-switched DNA synthesis (TS). DDT is regulated by ubiquitination of proliferating cell nuclear antigen that binds to...

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Detalles Bibliográficos
Autores principales: Hashimoto, Hiroshi, Hishiki, Asami, Hara, Kodai, Kikuchi, Sotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773155/
https://www.ncbi.nlm.nih.gov/pubmed/29362705
http://dx.doi.org/10.2142/biophysico.14.0_199