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SAXS analysis of a soluble cytosolic NgBR construct including extracellular and transmembrane domains

The Nogo-B receptor (NgBR) is involved in oncogenic Ras signaling through directly binding to farnesylated Ras. It recruits farnesylated Ras to the non-lipid-raft membrane for interaction with downstream effectors. However, the cytosolic domain of NgBR itself is only partially folded. The lack of se...

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Detalles Bibliográficos
Autores principales: Holcomb, Joshua, Doughan, Maysaa, Spellmon, Nicholas, Lewis, Brianne, Perry, Emerson, Zhang, Yingxue, Nico, Lindsey, Wan, Junmei, Chakravarthy, Srinivas, Shang, Weifeng, Miao, Qing, Stemmler, Timothy, Yang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773207/
https://www.ncbi.nlm.nih.gov/pubmed/29346419
http://dx.doi.org/10.1371/journal.pone.0191371