The mechanisms how heparin affects the tumor cell induced VEGF and chemokine release from platelets to attenuate the early metastatic niche formation

Metastasis is responsible for the majority of cancer associated fatalities. Tumor cells leaving the primary tumor and entering the blood flow immediately interact with platelets. Activated platelets contribute in different ways to cancer cell survival and proliferation, e.g. in formation of the earl...

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Detalles Bibliográficos
Autores principales: Ponert, Jan Moritz, Schwarz, Svenja, Haschemi, Reza, Müller, Jens, Pötzsch, Bernd, Bendas, Gerd, Schlesinger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773218/
https://www.ncbi.nlm.nih.gov/pubmed/29346400
http://dx.doi.org/10.1371/journal.pone.0191303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773218/
https://www.ncbi.nlm.nih.gov/pubmed/29346400
http://dx.doi.org/10.1371/journal.pone.0191303

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