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Infection and depletion of CD4(+) group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway
Innate lymphoid cells (ILCs) are severely depleted during chronic HIV-1 infection by unclear mechanisms. We report here that human ILC1s comprising of CD4(+) and CD4(-) subpopulations were present in various human lymphoid organs but with different transcription programs and functions. Importantly,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773236/ https://www.ncbi.nlm.nih.gov/pubmed/29304123 http://dx.doi.org/10.1371/journal.ppat.1006819 |