High response rate to PD-1 blockade in desmoplastic melanomas

Desmoplastic melanoma (DM) is a rare subtype of melanoma characterized by dense fibrous stroma, resistance to chemotherapy and a lack of actionable driver mutations, but is highly associated with ultraviolet light DNA damage.(1) We analysed 60 patients with advanced DM treated with programmed cell d...

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Detalles Bibliográficos
Autores principales: Eroglu, Zeynep, Zaretsky, Jesse M., Hu-Lieskovan, Siwen, Kim, Dae Won, Algazi, Alain, Johnson, Douglas B., Liniker, Elizabeth, Kong, Ben, Munhoz, Rodrigo, Rapisuwon, Suthee, Gherardini, Pier Federico, Chmielowski, Bartosz, Wang, Xiaoyan, Shintaku, I. Peter, Wei, Cody, Sosman, Jeffrey A., Joseph, Richard, Postow, Michael A., Carlino, Matteo S, Hwu, Wen-Jen, Scolyer, Richard A., Messina, Jane, Cochran, Alistair J., Long, Georgina V., Ribas, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773412/
https://www.ncbi.nlm.nih.gov/pubmed/29320474
http://dx.doi.org/10.1038/nature25187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773412/
https://www.ncbi.nlm.nih.gov/pubmed/29320474
http://dx.doi.org/10.1038/nature25187

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