Pharmacogenomics Study of Thiazide Diuretics and QT Interval in Multi-Ethnic Populations: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE)

Thiazide diuretics, commonly used antihypertensives, may cause QT interval (QT) prolongation, a risk factor for highly fatal and difficult to predict ventricular arrhythmias. We examined whether common SNPs modified the association between thiazide use and QT or its component parts (QRS interval, JT...

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Detalles Bibliográficos
Autores principales: Seyerle, Amanda A, Sitlani, Colleen M, Noordam, Raymond, Gogarten, Stephanie M, Li, Jin, Li, Xiaohui, Evans, Daniel S, Sun, Fangui, Laaksonen, Maarit A, Isaacs, Aaron, Kristiansson, Kati, Highland, Heather M, Stewart, James D, Harris, Tamara B, Trompet, Stella, Bis, Joshua C, Peloso, Gina M, Brody, Jennifer A, Broer, Linda, Busch, Evan L, Duan, Qing, Stilp, Adrienne M, O’Donnell, Christopher J, Macfarlane, Peter W, Floyd, James S, Kors, Jan A, Lin, Henry J, Li-Gao, Ruifang, Sofer, Tamar, Méndez-Giráldez, Raúl, Cummings, Steven R, Heckbert, Susan R, Hofman, Albert, Ford, Ian, Li, Yun, Launer, Lenore J, Porthan, Kimmo, Newton-Cheh, Christopher, Napier, Melanie D, Kerr, Kathleen F, Reiner, Alexander P, Rice, Kenneth M, Roach, Jeffrey, Buckley, Brendan M, Soliman, Elsayed Z, de Mutsert, Renée, Sotoodehnia, Nona, Uitterlinden, André G, North, Kari E, Lee, Craig R, Gudnason, Vilmundur, Stürmer, Til, Rosendaal, Frits R, Taylor, Kent D, Wiggins, Kerri L, Wilson, James G, Chen, Yii-Der I, Kaplan, Robert C, Wilhelmsen, Kirk, Cupples, L Adrienne, Salomaa, Veikko, van Duijn, Cornelia, Jukema, J Wouter, Liu, Yongmei, Mook-Kanamori, Dennis O, Lange, Leslie A, Vasan, Ramachandran S, Smith, Albert V, Stricker, Bruno H, Laurie, Cathy C, Rotter, Jerome I, Whitsel, Eric A, Psaty, Bruce M, Avery, Christy L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773415/
https://www.ncbi.nlm.nih.gov/pubmed/28719597
http://dx.doi.org/10.1038/tpj.2017.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773415/
https://www.ncbi.nlm.nih.gov/pubmed/28719597
http://dx.doi.org/10.1038/tpj.2017.10

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