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PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cord

BACKGROUND: Pyruvate kinase isozymes M2 (PKM2), as a member of pyruvate kinase family, plays a role of glycolytic enzyme in glucose metabolism. It also functions as protein kinase in cell proliferation, signaling, immunity, and gene transcription. In this study, the role of PKM2 in neuropathic pain...

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Detalles Bibliográficos
Autores principales: Wang, Binbin, Liu, Siyuan, Fan, Bingbing, Xu, Xingguo, Chen, Yonglin, Lu, Rongxiang, Xu, Zhongling, Liu, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773456/
https://www.ncbi.nlm.nih.gov/pubmed/29349661
http://dx.doi.org/10.1186/s10194-018-0836-4