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PKM2 is involved in neuropathic pain by regulating ERK and STAT3 activation in rat spinal cord
BACKGROUND: Pyruvate kinase isozymes M2 (PKM2), as a member of pyruvate kinase family, plays a role of glycolytic enzyme in glucose metabolism. It also functions as protein kinase in cell proliferation, signaling, immunity, and gene transcription. In this study, the role of PKM2 in neuropathic pain...
Autores principales: | Wang, Binbin, Liu, Siyuan, Fan, Bingbing, Xu, Xingguo, Chen, Yonglin, Lu, Rongxiang, Xu, Zhongling, Liu, Xiaojuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773456/ https://www.ncbi.nlm.nih.gov/pubmed/29349661 http://dx.doi.org/10.1186/s10194-018-0836-4 |
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