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Characterization of the impact of glutaredoxin-2 (GRX2) deficiency on superoxide/hydrogen peroxide release from cardiac and liver mitochondria
Mitochondria are critical sources of hydrogen peroxide (H(2)O(2)), an important secondary messenger in mammalian cells. Recent work has shown that O(2)(•-)/H(2)O(2) emission from individual sites of production in mitochondria is regulated by protein S-glutathionylation. Here, we conducted the first...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773472/ https://www.ncbi.nlm.nih.gov/pubmed/29274570 http://dx.doi.org/10.1016/j.redox.2017.12.006 |