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Activation of Ca(2+)-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

Cadmium (Cd), as an extremely toxic metal could accumulate in kidney and induce renal injury. Previous studies have proved that Cd impact on renal cell proliferation, autophagy and apoptosis, but the detoxification drugs and the functional mechanism are still in study. In this study, we used mouse r...

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Detalles Bibliográficos
Autores principales: Gu, Jie, Dai, Shuya, Liu, Yanmin, Liu, Haitao, Zhang, Yao, Ji, Xingqi, Yu, Feng, Zhou, Yang, Chen, Liang, Tse, William Ka Fai, Wong, Chris Kong Chu, Chen, Binghai, Shi, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773512/
https://www.ncbi.nlm.nih.gov/pubmed/29348484
http://dx.doi.org/10.1038/s41598-018-19327-9