Cargando…

Activation of Ca(2+)-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

Cadmium (Cd), as an extremely toxic metal could accumulate in kidney and induce renal injury. Previous studies have proved that Cd impact on renal cell proliferation, autophagy and apoptosis, but the detoxification drugs and the functional mechanism are still in study. In this study, we used mouse r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Jie, Dai, Shuya, Liu, Yanmin, Liu, Haitao, Zhang, Yao, Ji, Xingqi, Yu, Feng, Zhou, Yang, Chen, Liang, Tse, William Ka Fai, Wong, Chris Kong Chu, Chen, Binghai, Shi, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773512/ https://www.ncbi.nlm.nih.gov/pubmed/29348484 http://dx.doi.org/10.1038/s41598-018-19327-9

Ejemplares similares

Cadmium Disrupted ER Ca(2+) Homeostasis by Inhibiting SERCA2 Expression and Activity to Induce Apoptosis in Renal Proximal Tubular Cells
por: Li, Kongdong, et al.
Publicado: (2023)

Trehalose protects against cadmium-induced cytotoxicity in primary rat proximal tubular cells via inhibiting apoptosis and restoring autophagic flux
por: Wang, Xin-Yu, et al.
Publicado: (2017)

Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells
por: Fujiki, K, et al.
Publicado: (2014)

Cadmium Toxicity Is Regulated by Peroxisome Proliferator-Activated Receptor δ in Human Proximal Tubular Cells
por: Mori, Chikage, et al.
Publicado: (2022)

Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture
por: Liu, Gang, et al.
Publicado: (2016)

PARP-1 overexpression contributes to Cadmium-induced death in rat proximal tubular cells via parthanatos and the MAPK signalling pathway
por: Luo, Tongwang, et al.
Publicado: (2017)

Multigenerational Study of Chemically Induced Cytotoxicity and Proliferation in Cultures of Human Proximal Tubular Cells
por: Lash, Lawrence H., et al.
Publicado: (2014)

Overendocytosis of gold nanoparticles increases autophagy and apoptosis in hypoxic human renal proximal tubular cells
por: Ding, Fengan, et al.
Publicado: (2014)

A nomogram to predict cadmium-induced renal tubular dysfunction
por: Wang, Xinru, et al.
Publicado: (2020)

Is renal tubular cadmium toxicity clinically relevant?
por: Boonprasert, Kanyarat, et al.
Publicado: (2018)

Proximal Tubular Hypertrophy and Enlarged Glomerular and Proximal Tubular Urinary Space in Obese Subjects with Proteinuria
por: Tobar, Ana, et al.
Publicado: (2013)

Increased Endocytosis of Cadmium-Metallothionein through the 24p3 Receptor in an In Vivo Model with Reduced Proximal Tubular Activity
por: Zavala-Guevara, Itzel Pamela, et al.
Publicado: (2021)

Ischemic postconditioning inhibits apoptosis in an in vitro proximal tubular cell model
por: WENG, XIAODONG, et al.
Publicado: (2015)

Emerging roles of proximal tubular endocytosis in renal fibrosis
por: Chen, Min, et al.
Publicado: (2023)

Beclin-1-mediated Autophagy Protects Against Cadmium-activated Apoptosis via the Fas/FasL Pathway in Primary Rat Proximal Tubular Cell Culture
por: Liu, Gang, et al.
Publicado: (2017)

Receptor-Associated Protein Blocks Internalization and Cytotoxicity of Myeloma Light Chain in Cultured Human Proximal Tubular Cells
por: Sengul, Sule, et al.
Publicado: (2013)

Antigen Cross-Presentation by Murine Proximal Tubular Epithelial Cells Induces Cytotoxic and Inflammatory CD8(+) T Cells
por: Linke, Alexandra, et al.
Publicado: (2022)

Hypercalciuria switches Ca(2+) signaling in proximal tubular cells, induces oxidative damage to promote calcium nephrolithiasis
por: Shin, Samuel, et al.
Publicado: (2021)

Renal tubular dysfunction and abnormalities of calcium metabolism in cadmium workers
por: Kazantzis, George
Publicado: (1979)

Metabolic mechanisms of acute proximal tubular injury
por: Hall, Andrew M., et al.
Publicado: (2022)

No Cytotoxic and Inflammatory Effects of Empagliflozin and Dapagliflozin on Primary Renal Proximal Tubular Epithelial Cells under Diabetic Conditions In Vitro
por: Baer, Patrick C., et al.
Publicado: (2020)

Regulation of MUTYH, a DNA Repair Enzyme, in Renal Proximal Tubular Epithelial Cells
por: Lu, Jianping, et al.
Publicado: (2015)

Loss of tubular creatinine secretion as the only sign of tubular proximal cell dysfunction in light chain proximal tubulopathy: A case report
por: Stehlé, Thomas, et al.
Publicado: (2016)

Metabolomic Changes of Human Proximal Tubular Cell Line in High Glucose Environment
por: Wei, Pascal Zhongping, et al.
Publicado: (2019)

Long-term observations on tubular and glomerular function in cadmium-exposed persons.
por: Piscator, M
Publicado: (1984)

Estimation of Benchmark Dose of Cumulative Cadmium Exposure for Renal Tubular Effect
por: Nogawa, Kazuhiro, et al.
Publicado: (2021)

Proximal Tubular Cell–Specific Ablation of Carnitine Acetyltransferase Causes Tubular Disease and Secondary Glomerulosclerosis
por: Kruger, Claudia, et al.
Publicado: (2019)

Motile Cilia on Kidney Proximal Tubular Epithelial Cells Are Associated With Tubular Injury and Interstitial Fibrosis
por: Eymael, Jennifer, et al.
Publicado: (2022)

Sodium and Water Transport in Kidney Proximal Tubular Cells
por: Whittembury, Guillermo
Publicado: (1968)

Ex vivo analysis of renal proximal tubular cells
por: Legouis, David, et al.
Publicado: (2015)

Proximal renal tubular acidosis with and without Fanconi syndrome
por: Kashoor, Ibrahim, et al.
Publicado: (2019)

Assessment of kidney proximal tubular secretion in critical illness
por: Bhatraju, Pavan K., et al.
Publicado: (2021)

The new insights into cadmium sensing
por: Chmielowska-Bąk, Jagna, et al.
Publicado: (2014)

Unexpected Enhancement of Cytotoxicity of Cisplatin in a Rat Kidney Proximal Tubular Cell Line Overexpressing Mitochondrial Glutathione Transport Activity
por: Lash, Lawrence H.
Publicado: (2022)

Abrogation of store-operated Ca(2+) entry protects against crystal-induced ER stress in human proximal tubular cells
por: Gombedza, Farai C., et al.
Publicado: (2019)

Pressure and stretch differentially affect proliferation of renal proximal tubular cells
por: Felsen, Diane, et al.
Publicado: (2017)

Construction of Mode of Action for Cadmium-Induced Renal Tubular Dysfunction Based on a Toxicity Pathway-Oriented Approach
por: Zhang, Yangchun, et al.
Publicado: (2021)

CaMKII is involved in subcellular Ca(2+) redistribution-induced endoplasmic reticulum stress leading to apoptosis in primary cultures of rat proximal tubular cells exposed to lead
por: Wang, Min-Ge, et al.
Publicado: (2017)

Tubular and Glomerular Kidney Effects in Swedish Women with Low Environmental Cadmium Exposure
por: Åkesson, Agneta, et al.
Publicado: (2005)

Cadmium and lead in blood in relation to low bone mineral density and tubular proteinuria.
por: Alfvén, Tobias, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_4rqetoi4u130spb3lm13m4antq