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GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21

Childhood acute lymphoblastic leukemia (ALL) (age 0–14 years) is 20% more common in Latino Americans than non-Latino whites. We conduct a genome-wide association study in a large sample of 3263 Californian children with ALL (including 1949 of Latino heritage) and 3506 controls matched on month and y...

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Detalles Bibliográficos
Autores principales: Wiemels, Joseph L., Walsh, Kyle M., de Smith, Adam J., Metayer, Catherine, Gonseth, Semira, Hansen, Helen M., Francis, Stephen S., Ojha, Juhi, Smirnov, Ivan, Barcellos, Lisa, Xiao, Xiaorong, Morimoto, Libby, McKean-Cowdin, Roberta, Wang, Rong, Yu, Herbert, Hoh, Josephine, DeWan, Andrew T., Ma, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773513/
https://www.ncbi.nlm.nih.gov/pubmed/29348612
http://dx.doi.org/10.1038/s41467-017-02596-9