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Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells

Many cell lines derived from solid cancers can form spheroids, which recapitulate tumor cell clusters and are more representative of the in vivo situation than 2D cultures. During spheroid formation, a small proportion of a variety of different colon cancer cell lines did not integrate into the sphe...

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Detalles Bibliográficos
Autores principales: Stadler, Mira, Scherzer, Martin, Walter, Stefanie, Holzner, Silvio, Pudelko, Karoline, Riedl, Angelika, Unger, Christine, Kramer, Nina, Weil, Beatrix, Neesen, Jürgen, Hengstschläger, Markus, Dolznig, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773514/
https://www.ncbi.nlm.nih.gov/pubmed/29348601
http://dx.doi.org/10.1038/s41598-018-19384-0