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Dynamic cellular maps of molecular species: Application to drug-target interactions

The design of living cell studies aimed at deciphering the mechanism of action of drugs targeting proteins with multiple functions, expressed in a wide range of concentrations and cellular locations, is a real challenge. We recently showed that the antitumor drug plitidepsin (APL) localizes sufficie...

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Detalles Bibliográficos
Autores principales: García, Carolina, Losada, Alejandro, Sacristán, Miguel A., Martínez-Leal, Juan Fernando, Galmarini, Carlos M., Lillo, M. Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773516/
https://www.ncbi.nlm.nih.gov/pubmed/29348621
http://dx.doi.org/10.1038/s41598-018-19694-3