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Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan

Malaria, caused by parasites of the genus Plasmodium, leads to over half a million deaths per year, 90% of which are caused by Plasmodium falciparum. P. vivax usually causes milder forms of malaria; however, P. vivax can remain dormant in the livers of infected patients for weeks or years before re-...

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Detalles Bibliográficos
Autores principales: Bilsland, Elizabeth, van Vliet, Liisa, Williams, Kevin, Feltham, Jack, Carrasco, Marta P., Fotoran, Wesley L., Cubillos, Eliana F. G., Wunderlich, Gerhard, Grøtli, Morten, Hollfelder, Florian, Jackson, Victoria, King, Ross D., Oliver, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773535/
https://www.ncbi.nlm.nih.gov/pubmed/29348637
http://dx.doi.org/10.1038/s41598-018-19549-x