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v-Src-driven transformation is due to chromosome abnormalities but not Src-mediated growth signaling

v-Src is the first identified oncogene product and has a strong tyrosine kinase activity. Much of the literature indicates that v-Src expression induces anchorage-independent and infinite cell proliferation through continuous stimulation of growth signaling by v-Src activity. Although all of v-Src-e...

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Detalles Bibliográficos
Autores principales: Honda, Takuya, Morii, Mariko, Nakayama, Yuji, Suzuki, Ko, Yamaguchi, Noritaka, Yamaguchi, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773541/
https://www.ncbi.nlm.nih.gov/pubmed/29348492
http://dx.doi.org/10.1038/s41598-018-19599-1