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v-Src-driven transformation is due to chromosome abnormalities but not Src-mediated growth signaling
v-Src is the first identified oncogene product and has a strong tyrosine kinase activity. Much of the literature indicates that v-Src expression induces anchorage-independent and infinite cell proliferation through continuous stimulation of growth signaling by v-Src activity. Although all of v-Src-e...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773541/ https://www.ncbi.nlm.nih.gov/pubmed/29348492 http://dx.doi.org/10.1038/s41598-018-19599-1 |