Cromolyn Reduces Levels of the Alzheimer’s Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis

Amyloid-beta protein (Aβ) deposition is a pathological hallmark of Alzheimer’s disease (AD). Aβ deposition triggers both pro-neuroinflammatory microglial activation and neurofibrillary tangle formation. Cromolyn sodium is an asthma therapeutic agent previously shown to reduce Aβ levels in transgenic...

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Detalles Bibliográficos
Autores principales: Zhang, Can, Griciuc, Ana, Hudry, Eloise, Wan, Yu, Quinti, Luisa, Ward, Joseph, Forte, Angela M., Shen, Xunuo, Ran, ChongZhao, Elmaleh, David R., Tanzi, Rudolph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773545/
https://www.ncbi.nlm.nih.gov/pubmed/29348604
http://dx.doi.org/10.1038/s41598-018-19641-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773545/
https://www.ncbi.nlm.nih.gov/pubmed/29348604
http://dx.doi.org/10.1038/s41598-018-19641-2

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