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Chikungunya virus nsP1 interacts directly with nsP2 and modulates its ATPase activity

Chikungunya virus (CHIKV) is a mosquito-borne virus, which has created an alarming threat in the world due to unavailability of vaccine and antiviral compounds. The CHIKV nsP2 contains ATPase, RTPase, helicase and protease activities, whereas, nsP1 is a viral capping enzyme. In alphaviruses, the fou...

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Detalles Bibliográficos
Autores principales: Kumar, Sameer, Kumar, Abhishek, Mamidi, Prabhudutta, Tiwari, Atul, Kumar, Sriram, Mayavannan, Animamalar, Mudulli, Sagarika, Singh, Ajit Kumar, Subudhi, Bharat Bhusan, Chattopadhyay, Soma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773547/
https://www.ncbi.nlm.nih.gov/pubmed/29348627
http://dx.doi.org/10.1038/s41598-018-19295-0