Intradermal delivery of STAT3 siRNA to treat melanoma via dissolving microneedles

Hyperactivity of signal transducer and activity of transcription 3 (STAT3) plays a crucial role in melanoma invasion and metastasis. Gene therapy applying siRNA targeting STAT3 is a potential therapeutic strategy for melanoma. In this article, we first fabricated safe and novel dissolving microneedl...

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Detalles Bibliográficos
Autores principales: Pan, Jingtong, Ruan, Wenyi, Qin, Mengyao, Long, Yueming, Wan, Tao, Yu, Kaiyue, Zhai, Yuanhao, Wu, Chuanbin, Xu, Yuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773564/
https://www.ncbi.nlm.nih.gov/pubmed/29348670
http://dx.doi.org/10.1038/s41598-018-19463-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773564/
https://www.ncbi.nlm.nih.gov/pubmed/29348670
http://dx.doi.org/10.1038/s41598-018-19463-2

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