Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice

The formation of amyloid fibrils by human islet amyloid polypeptide protein (hIAPP) has been implicated in pancreas dysfunction and diabetes. However, efficient treatment options to reduce amyloid fibrils in vivo are still lacking. Therefore, we tested the effect of epigallocatechin gallate (EGCG) o...

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Detalles Bibliográficos
Autores principales: Franko, Andras, Rodriguez Camargo, Diana C., Böddrich, Annett, Garg, Divita, Rodriguez Camargo, Andres, Rathkolb, Birgit, Janik, Dirk, Aichler, Michaela, Feuchtinger, Annette, Neff, Frauke, Fuchs, Helmut, Wanker, Erich E., Reif, Bernd, Häring, Hans-Ulrich, Peter, Andreas, Hrabě de Angelis, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773570/
https://www.ncbi.nlm.nih.gov/pubmed/29348618
http://dx.doi.org/10.1038/s41598-017-18807-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773570/
https://www.ncbi.nlm.nih.gov/pubmed/29348618
http://dx.doi.org/10.1038/s41598-017-18807-8

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