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Redundancy of protein disulfide isomerases in the catalysis of the inactivating disulfide switch in A Disintegrin and Metalloprotease 17
A Disintegrin and Metalloprotease 17 (ADAM17) can cause the fast release of growth factors and inflammatory mediators from the cell surface. Its activity has to be turned on which occurs by various stimuli. The active form can be inactivated by a structural change in its ectodomain, related to the p...
Autores principales: | Krossa, Sebastian, Scheidig, Axel J., Grötzinger, Joachim, Lorenzen, Inken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773583/ https://www.ncbi.nlm.nih.gov/pubmed/29348576 http://dx.doi.org/10.1038/s41598-018-19429-4 |
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