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Noise-induced bistability in the fate of cancer phenotypic quasispecies: a bit-strings approach
Tumor cell populations are highly heterogeneous. Such heterogeneity, both at genotypic and phenotypic levels, is a key feature during tumorigenesis. How to investigate the impact of this heterogeneity in the dynamics of tumors cells becomes an important issue. Here we explore a stochastic model desc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773630/ https://www.ncbi.nlm.nih.gov/pubmed/29348614 http://dx.doi.org/10.1038/s41598-018-19552-2 |