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Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes

There is a large demand of a human relevant in vitro test system suitable for assessing the cardiotoxic potential of cosmetic ingredients and other chemicals. Using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), we have already established an in vitro cardiotoxicity assay an...

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Detalles Bibliográficos
Autores principales: Chaudhari, Umesh, Nemade, Harshal, Sureshkumar, Poornima, Vinken, Mathieu, Ates, Gamze, Rogiers, Vera, Hescheler, Jürgen, Hengstler, Jan Georg, Sachinidis, Agapios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773645/
https://www.ncbi.nlm.nih.gov/pubmed/28940058
http://dx.doi.org/10.1007/s00204-017-2065-z