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Genome-wide mapping and analysis of aryl hydrocarbon receptor (AHR)- and aryl hydrocarbon receptor repressor (AHRR)-binding sites in human breast cancer cells

The aryl hydrocarbon receptor (AHR) mediates the toxic actions of environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (TCDD), and also plays roles in vascular development, the immune response, and cell cycle regulation. The AHR repressor (AHRR) is an AHR-regulated gene and a nega...

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Detalles Bibliográficos
Autores principales: Yang, Sunny Y., Ahmed, Shaimaa, Satheesh, Somisetty V., Matthews, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773648/
https://www.ncbi.nlm.nih.gov/pubmed/28681081
http://dx.doi.org/10.1007/s00204-017-2022-x