Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo

Bacterial protein toxins became valuable molecular tools for the targeted modulation of cell functions in experimental pharmacology and attractive therapeutics because of their potent and specific mode of action in human cells. C2IN-C3lim, a recombinant fusion toxin (~50 kDa) of the Rho-inhibiting C...

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Detalles Bibliográficos
Autores principales: Martin, Tobias, Möglich, Amelie, Felix, Ina, Förtsch, Christina, Rittlinger, Anne, Palmer, Annette, Denk, Stephanie, Schneider, Julian, Notbohm, Lena, Vogel, Mona, Geiger, Hartmut, Paschke, Stephan, Huber-Lang, Markus, Barth, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773661/
https://www.ncbi.nlm.nih.gov/pubmed/28924833
http://dx.doi.org/10.1007/s00204-017-2058-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773661/
https://www.ncbi.nlm.nih.gov/pubmed/28924833
http://dx.doi.org/10.1007/s00204-017-2058-y

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