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Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients

BACKGROUND: Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics. METHODS: We did an individual patient-level data meta-analysis of randomised trials done with more than 1000 patients t...

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Detalles Bibliográficos
Autores principales: Gayet-Ageron, Angèle, Prieto-Merino, David, Ker, Katharine, Shakur, Haleema, Ageron, François-Xavier, Roberts, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773762/
https://www.ncbi.nlm.nih.gov/pubmed/29126600
http://dx.doi.org/10.1016/S0140-6736(17)32455-8