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Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients
BACKGROUND: Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics. METHODS: We did an individual patient-level data meta-analysis of randomised trials done with more than 1000 patients t...
Autores principales: | Gayet-Ageron, Angèle, Prieto-Merino, David, Ker, Katharine, Shakur, Haleema, Ageron, François-Xavier, Roberts, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773762/ https://www.ncbi.nlm.nih.gov/pubmed/29126600 http://dx.doi.org/10.1016/S0140-6736(17)32455-8 |
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