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The age-related changes of dietary phosphate responsiveness in plasma 1,25-dihydroxyvitamin D levels and renal Cyp27b1 and Cyp24a1 gene expression is associated with renal α-Klotho gene expression in mice

In this study, we investigated the relationship between age-related changes in renal α-Klotho gene expression, vitamin D metabolism and the responsiveness of dietary phosphate in 1, 2 and 13 month-old mice fed a high phosphate (phosphate 1.2%) diet or low phosphate (phosphate 0.02%) diet for 5 days....

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Detalles Bibliográficos
Autores principales: Yoshikawa, Ryouhei, Yamamoto, Hironori, Nakahashi, Otoki, Kagawa, Tomohiro, Tajiri, Mari, Nakao, Mari, Fukuda, Shiori, Arai, Hidekazu, Masuda, Masashi, Iwano, Masayuki, Takeda, Eiji, Taketani, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773827/
https://www.ncbi.nlm.nih.gov/pubmed/29371756
http://dx.doi.org/10.3164/jcbn.17-20